Suggestion 1:
I would like to have a keyboard shortcut for the "Jump" toolbar button in the register window.

As of version 2.4.10, I have to use the mouse to jump between corresponding accounts, either by clicking the "Jump" button, or by right-cliking and selecting the "Jump" menu item at the bottom.

I propose the use of Ctrl+Right and/or Left Arrow Keys for this command so that it can be executed with the right hand alone with minimal physical effort.

Switching between Basic Legder, Auto-Split Ledger and Transaction Journal views can be done similarly with Ctrl+Up/Down Arrow keys

Suggestion 2:
the ESC-key should do the same as the "Cancel" toolbar button.

To summarize - GnuCash should be usable even if the battery on your wireless mouse dies.